Renegade is a port of Taito's single-player arcade classic that started it all. You fight small waves of relatively powerful enemies with a large moveset before fighting a boss in each of four stages. This port adds new areas, a motorcycle combat section, and a redesigned labyrinth-like final stage.
This is the US version of Nekketsu Kouha Kunio-kun, which features different graphics and characters but plays the same.
This is the first NES brawler, and the original Rengade was the first brawler ever made.
Renegade is the best. It'll undoubtedly turn off most players at first, but once you learn how its combat works it's pure joy. The unbelievably huge movesets were way ahead of its time, and the face-punch attack is infinitely satisfying. The graphics are awful, but the music's super catchy and memorable. The labyrinth is dubious, though.